Journal of Clinical Endocrinology and Diabetes Research

Serum Levels of Creatinine in Newly Diagnosed Type 2 Diabetics with hypertension of Karnataka State, South India

Author(s): Sujatha Narayana Rao*, Kuldeep GB, Mukesh Sharma

Background: Type 2 Diabetes Mellitus is the biggest silent lifestyle epidemic in the human history. Kidney disease is one of its long-term complications.It warrants an immediate attention for research.

Aim: This study aims to evaluate the levels of serum creatinine in healthy, newly diagnosed (N.D.) Type 2 Diabetics, N.D. type 2 Diabetics with hypertension and in Diabetics with Nephropathy to explore the pattern of Serum Creatinine levels.

Method: In a study involving a total of 297 Individuals of Bangalore, Karnataka State, South India, Glycated hemoglobin (HbA1c) and serum creatinine were estimated in the above 4 groups. Results were analyzed by Statistical Analysis version 24- ANOVA & Tukey’s post hoc test.

Result: Significantly higher serum Creatinine levels in N.D. type 2 Diabetics with hypertension group than healthy group and significantly higher creatinine levels in Diabetic Nephropathy group than N.D. Type 2 Diabetics with Hypertension group were noted.

Conclusion: Serum creatinine levels were gradually increasing from Healthy to N.D. Type 2 Diabetics and then to N.D. Type 2 Diabetics with hypertension and the highest level was noted in diabetics with nephropathy. So, regular monitoring of creatinine levels among hypertensive diabetics is needed to prevent further complications like diabetic nephropathy in them.